ICSC 1372 - TETRAHYDROPHTHALIC ANHYDRIDE

« back to the search result list

TETRAHYDROPHTHALIC ANHYDRIDE	ICSC: 1372 (April 2024)
4-Cyclohexene-1,2-dicarboxylic anhydride 3a,4,7,7a-Tetrahydro-1,3-isobenzofurandione THPA 1,2,3,6-Tetrahydrophthalic anhydride

CAS #: 85-43-8

UN #: 2698 (see Notes)

EC Number: 201-605-4

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Finely dispersed particles form explosive mixtures in air.	NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.	Use water spray, powder, foam, carbon dioxide.

AVOID ALL CONTACT! PREVENT DISPERSION OF DUST!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Wheezing. Shortness of breath.	Use local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	Redness. Burning sensation.	Protective gloves. Protective clothing.	Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse skin with plenty of water or shower for at least 15 minutes.
Eyes	Redness. Pain. Blurred vision. Corneal damage.	Wear safety goggles or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Burning sensation. Abdominal pain.	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus, face shield and protective gloves. If appropriate, moisten first to prevent dusting. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.	According to UN GHS Criteria DANGER May cause allergy or asthma symptoms or breathing difficulties if inhaled May cause an allergic skin reaction Causes serious eye damage Harmful to aquatic life Transportation UN Classification UN Hazard Class: 8; UN Pack Group: III
STORAGE
Separated from food and feedstuffs and oxidants. Store only in original container. Dry. Well closed. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs.

TETRAHYDROPHTHALIC ANHYDRIDE

ICSC: 1372

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE CRYSTALLINE POWDER. Physical dangers Dust explosion possible if in powder or granular form, mixed with air. Chemical dangers Decomposes on contact with hot surfaces or flames. This produces corrosive fumes. Reacts with oxidants. Reacts with water. This produces heat and tetrahydrophthalic acid.	Formula: C₈H₈O₃ / C₆H₈(CO)₂O Molecular mass: 152.2 Boiling point at 6.7kPa: 195°C Melting point: 102°C Density: 1.4 g/cm³ Solubility in water, g/l at 20°C: 29.4 (reaction) Vapour pressure, Pa at 20°C: 1 Relative vapour density (air = 1): 5.3 Flash point: 157°C o.c. Auto-ignition temperature: 450°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALLINE POWDER.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces corrosive fumes. Reacts with oxidants. Reacts with water. This produces heat and tetrahydrophthalic acid.

Formula: C₈H₈O₃ / C₆H₈(CO)₂O
Molecular mass: 152.2
Boiling point at 6.7kPa: 195°C
Melting point: 102°C
Density: 1.4 g/cm³
Solubility in water, g/l at 20°C: 29.4 (reaction)
Vapour pressure, Pa at 20°C: 1
Relative vapour density (air = 1): 5.3
Flash point: 157°C o.c.
Auto-ignition temperature: 450°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. Effects of short-term exposure The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract.	Inhalation risk A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. Effects of long-term or repeated exposure Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract.

Inhalation risk
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT
The substance is harmful to aquatic organisms.

NOTES
Phthalic anhydride in the solid state and tetra–hydrophthalic anhydrides, with not more than 0.05% maleic anhydride, are not subject to transport regulations. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact. Do NOT take working clothes home.

NOTES

Phthalic anhydride in the solid state and tetra–hydrophthalic anhydrides, with not more than 0.05% maleic anhydride, are not subject to transport regulations.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
Do NOT take working clothes home.

ADDITIONAL INFORMATION

EC Classification

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.