ICSC 1158 - TETRAETHYL PYROPHOSPHATE

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TETRAETHYL PYROPHOSPHATE	ICSC: 1158 (April 2017)
TEPP Diphosphoric acid, tetraethyl ester Tetraethyl diphosphate

CAS #: 107-49-3

UN #: 3018

EC Number: 203-495-3

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion if formulations contain flammable/explosive solvents.	NO open flames.	Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

AVOID ALL CONTACT! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! FIRST AID: USE PERSONAL PROTECTION. IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Dizziness. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Laboured breathing. Cough. Weakness. Abdominal cramps. Diarrhoea. Nausea. Vomiting. Incoordination. Convulsions. Unconsciousness.	Use ventilation, local exhaust or breathing protection.	Remove immediately from exposure. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention. See Notes.
Skin	EASILY ABSORBED! Redness. Pain. Further see Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. See Notes. Refer immediately for medical attention.
Eyes	Redness. Pain. Blurred vision.	Wear face shield or eye protection in combination with breathing protection.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Do NOT induce vomiting. See Notes. Give a slurry of activated charcoal in water to drink, but NOT if convulsions occur. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable non-metallic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Fatal if swallowed or in contact with skin Causes skin and eye irritation Causes damage to nervous system Causes damage to the nervous system through prolonged or repeated exposure Very toxic to aquatic life Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: I
STORAGE
Store only in original container. Separated from food and feedstuffs. Keep in a well-ventilated room. Dry. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
PACKAGING
Do not transport with food and feedstuffs. Marine pollutant.

TETRAETHYL PYROPHOSPHATE

ICSC: 1158

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS HYGROSCOPIC LIQUID. Physical dangers Chemical dangers Decomposes above 170°C . This produces flammable gas (ethylene) and toxic fumes including phosphorous oxides. Attacks some forms of plastic, rubber and coatings. The substance is corrosive to most metals.	Formula: C₈H₂₀O₇P₂ / (C₂H₅O)₂-PO-O-PO-(OC₂H₅)₂ Molecular mass: 290.2 Density: 1.18 g/cm³ Solubility in water: good Vapour pressure, Pa at 20°C: 2 Relative vapour density (air = 1): 10 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: >110°C c.c. Octanol/water partition coefficient as log Pow: 2.94

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS HYGROSCOPIC LIQUID.

Physical dangers

Chemical dangers
Decomposes above 170°C . This produces flammable gas (ethylene) and toxic fumes including phosphorous oxides. Attacks some forms of plastic, rubber and coatings. The substance is corrosive to most metals.

Formula: C₈H₂₀O₇P₂ / (C₂H₅O)₂-PO-O-PO-(OC₂H₅)₂
Molecular mass: 290.2
Density: 1.18 g/cm³
Solubility in water: good
Vapour pressure, Pa at 20°C: 2
Relative vapour density (air = 1): 10
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: >110°C c.c.
Octanol/water partition coefficient as log Pow: 2.94

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance is irritating to the eyes and skin. The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. See Acute Hazards/Symptoms. This may result in convulsions, respiratory failure, heart failure and death. Medical observation is indicated.	Inhalation risk A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C , on spraying much faster. Effects of long-term or repeated exposure Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the nervous system by a cholinesterase inhibiting effect. See Acute Hazards/Symptoms. This may result in convulsions, respiratory failure, heart failure and death. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C , on spraying much faster.

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

OCCUPATIONAL EXPOSURE LIMITS
TLV: (inhalable fraction): 0.01 mg/m³, as TWA; (skin); BEI issued. MAK: 0.060 mg/m³, 0.005 ppm; peak limitation category: II(2); skin absorption (H)

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to mammals, birds and bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Carrier solvents used in commercial formulations may change physical and toxicological properties. Isolate contaminated clothing by sealing in a bag or other container. Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home.

NOTES

Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
Isolate contaminated clothing by sealing in a bag or other container.
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.

ADDITIONAL INFORMATION

EC Classification
Symbol: T+, N; R: 27/28-50; S: (1/2)-36/37/39-38-45-61

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