ICSC 0578 - TETRAHYDROFURAN

« back to the search result list

TETRAHYDROFURAN	ICSC: 0578 (November 2019)
Tetramethylene oxide Diethylene oxide 1,4-Epoxybutane Oxacyclopentane

CAS #: 109-99-9

UN #: 2056

EC Number: 203-726-8

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Highly flammable. Vapour/air mixtures are explosive.	NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.	Use alcohol-resistant foam, water spray, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

PREVENT GENERATION OF MISTS! STRICT HYGIENE!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Burning sensation in the throat and chest. Dizziness. Headache. Nausea. Unconsciousness.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer immediately for medical attention.
Skin	Dry skin. Redness. Pain.	Protective gloves. Protective clothing.	First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .
Eyes	Redness. Pain.	Wear safety goggles or face shield.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work.	Rinse mouth. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Ventilation. Do NOT wash away into sewer. Collect leaking liquid in sealable air tight containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Highly flammable liquid and vapour Harmful if swallowed Causes skin irritation Causes serious eye irritation May cause respiratory irritation Suspected of causing cancer May cause damage to kidneys and liver through prolonged or repeated exposure Transportation UN Classification UN Hazard Class: 3; UN Pack Group: II
STORAGE
Fireproof. Well closed. Separated from : see Chemical Dangers.
PACKAGING
Airtight.

TETRAHYDROFURAN

ICSC: 0578

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Physical dangers The vapour is heavier than air and may travel along the ground; distant ignition possible. Chemical dangers The substance can form explosive peroxides. Reacts violently with strong oxidants, strong bases and some metal halides. This generates fire and explosion hazard. Attacks some forms of plastic, rubber and coatings.	Formula: C₄H₈O / (CH₂)₃CH₂O Molecular mass: 72.1 Boiling point: 66°C Melting point: -108.5°C Relative density (water = 1): 0.89 Solubility in water: freely soluble Vapour pressure, kPa at 20°C: 19.3 Relative vapour density (air = 1): 2.5 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.28 Flash point: -14.5°C c.c. Auto-ignition temperature: 321°C Explosive limits, vol% in air: 2-11.8 Octanol/water partition coefficient as log Pow: 0.46 (estimated) Viscosity: 0.5 mPa*s at 20°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
The substance can form explosive peroxides. Reacts violently with strong oxidants, strong bases and some metal halides. This generates fire and explosion hazard. Attacks some forms of plastic, rubber and coatings.

Formula: C₄H₈O / (CH₂)₃CH₂O
Molecular mass: 72.1
Boiling point: 66°C
Melting point: -108.5°C
Relative density (water = 1): 0.89
Solubility in water: freely soluble
Vapour pressure, kPa at 20°C: 19.3
Relative vapour density (air = 1): 2.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.28
Flash point: -14.5°C c.c.
Auto-ignition temperature: 321°C
Explosive limits, vol% in air: 2-11.8
Octanol/water partition coefficient as log Pow: 0.46 (estimated)
Viscosity: 0.5 mPa*s at 20°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour, by ingestion and through the skin. Effects of short-term exposure The substance and the vapour are irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system at high levels. This may result in narcosis.	Inhalation risk A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver and kidneys. This may result in impaired functions. This substance is possibly carcinogenic to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, by ingestion and through the skin.

Effects of short-term exposure
The substance and the vapour are irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system at high levels. This may result in narcosis.

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver and kidneys. This may result in impaired functions. This substance is possibly carcinogenic to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 50 ppm as TWA; 100 ppm as STEL; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: 150 mg/m³, 50 ppm; peak limitation category: I(2); skin absorption (H); carcinogen category: 4; pregnancy risk group: C. EU-OEL: 150 mg/m³, 50 ppm as TWA; 300 mg/m³, 100 ppm as STEL; (skin)

ENVIRONMENT

NOTES
The odour warning when the exposure limit value is exceeded is insufficient. Check for peroxides prior to distillation; eliminate if found.

ADDITIONAL INFORMATION

EC Classification

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.