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ARSENIC PENTOXIDEICSC: 0377 (April 2013)
Arsenic (V) oxide
Arsenic acid anhydride
Arsenic anhydride
Diarsenic pentoxide
CAS #: 1303-28-2
UN #: 1559
EC Number: 215-116-9

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.        In case of fire in the surroundings, use appropriate extinguishing media.   

 PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Headache. Dizziness. Weakness. Shortness of breath. Chest pain. See Notes. See Ingestion.  Use closed system and breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin Redness. Burning sensation. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion Vomiting. Abdominal pain. Diarrhoea. Severe thirst. Muscle cramps. Shock or collapse. Symptoms may be delayed.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer immediately for medical attention. See Notes. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health haz
DANGER
Fatal if swallowed
Causes skin and eye irritation
Suspected of causing genetic defects
May cause cancer
May damage fertility or the unborn child
Causes damage to the bone marrow, the blood, the cardiovascular system, the nervous system, the liver and the kidneys through prolonged or repeated exposure
Toxic to aquatic life 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from strong bases, reducing agents and food and feedstuffs. Dry. Well closed. 
PACKAGING
Unbreakable packaging.
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
Marine pollutant. 
ARSENIC PENTOXIDE ICSC: 0377
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE HYGROSCOPIC POWDER. 

Physical dangers
 

Chemical dangers
Decomposes above 300°C . This produces toxic fumes (arsenic trioxide - see ICSC 0378) and oxygen. The solution in water is a weak acid. Reacts violently with bromine pentafluoride. This generates fire and explosion hazard. Reacts with reducing agents. This produces very toxic gas (arsine - see ICSC 0222). Attacks many metals in the presence of water or moisture. 

Formula: As2O5
Molecular mass: 229.8
Decomposes at 315°C
Density: 4.3 g/cm³
Solubility in water, g/100ml at 20°C: 65.8 (good) 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Effects of short-term exposure
The substance and the aerosol are irritating to the eyes, respiratory tract and skin. The substance may cause effects on the blood, cardiovascular system, liver and central nervous system. The effects may be delayed. See Notes. Medical observation is indicated. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. 

Effects of long-term or repeated exposure
The substance may have effects on the skin (hyperkeratosis), cardiovascular system, bone marrow (hematopoietic changes), central nervous system, peripheral nervous system, kidneys and liver. This substance is carcinogenic to humans. Causes toxicity to human reproduction or development. 


OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.01 mg/m3, as TWA; A1 (confirmed human carcinogen); BEI issued.
MAK: skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A.
EU-OEL: (inhalable fraction): 0.01 mg/m3 as TWA; (see Notes) 

ENVIRONMENT
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Do NOT take working clothes home.
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of acute poisoning do not become manifest until 0.5 to several hours.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The recommendations on this Card also apply to inorganic pentavalent arsenic compounds (arsenates).
For the copper smelting sector, the EU OEL value shall apply from 11 July 2023. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 45-23/25-50/53; S: 53-45-60-61; Note: E 

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