ICSC 0326 - DISODIUM ARSENATE HEPTAHYDRATE

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DISODIUM ARSENATE HEPTAHYDRATE	ICSC: 0326 (November 2016)
Arsenic acid, disodium salt, heptahydrate Sodium arsenate heptahydrate Sodium arsenate, dibasic, heptahydrate

CAS #: 10048-95-0

UN #: 1685

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion on contact with metals. See Chemical Dangers.		In case of fire in the surroundings, use appropriate extinguishing media.

PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Headache. Sore throat. Weakness. Further see Ingestion.	Use closed system or ventilation.	Fresh air, rest. Refer for medical attention.
Skin	Redness. Pain.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Burning sensation. Diarrhoea. Vomiting. Shock or collapse.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria Toxic if swallowed Causes eye irritation May cause cancer Suspected of damaging fertility or the unborn child Causes damage to organs Causes damage to organs through prolonged or repeated exposure May cause long lasting harmful effects to aquatic life Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Store in an area without drain or sewer access. Well closed. Separated from acids and food and feedstuffs.
PACKAGING
Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Marine pollutant.

DISODIUM ARSENATE HEPTAHYDRATE

ICSC: 0326

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS CRYSTALS. Physical dangers Chemical dangers Decomposes on heating. This produces toxic fumes. Reacts with acids. This produces toxic arsine gas (see ICSC 0222). Attacks many metals such as iron, aluminium and zinc in the presence of water. This produces toxic fumes of arsenic and arsine.	Formula: Na₂HAsO₄. 7H₂O Molecular mass: 312.0 Decomposes at 180°C Melting point: 130°C Density: 1.9 g/cm³ Solubility in water, g/100ml at 21°C: 39

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS CRYSTALS.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic fumes. Reacts with acids. This produces toxic arsine gas (see ICSC 0222). Attacks many metals such as iron, aluminium and zinc in the presence of water. This produces toxic fumes of arsenic and arsine.

Formula: Na₂HAsO₄. 7H₂O
Molecular mass: 312.0
Decomposes at 180°C
Melting point: 130°C
Density: 1.9 g/cm³
Solubility in water, g/100ml at 21°C: 39

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the cardiovascular system, central nervous system, gastrointestinal tract and kidneys. This may result in cardiac disorders, severe gastroenteritis, loss of fluids and electrolytes, kidney impairment, collapse and shock. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful concentration of airborne particles can be reached quickly when dispersed. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the peripheral nervous system, mucous membranes, skin, cardiovascular system, bone marrow, kidneys and liver. This may result in neuropathy, pigmentation disorders, perforation of the nasal septum, lesions of blood cells, kidney impairment and cirrhosis. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the cardiovascular system, central nervous system, gastrointestinal tract and kidneys. This may result in cardiac disorders, severe gastroenteritis, loss of fluids and electrolytes, kidney impairment, collapse and shock. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the peripheral nervous system, mucous membranes, skin, cardiovascular system, bone marrow, kidneys and liver. This may result in neuropathy, pigmentation disorders, perforation of the nasal septum, lesions of blood cells, kidney impairment and cirrhosis. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.01 mg/m³, as TWA; A1 (confirmed human carcinogen); BEI issued. MAK: skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A. EU-OEL: (inhalable fraction): 0.01 mg/m³ as TWA; (see Notes)

ENVIRONMENT
This substance may be hazardous to the environment. Special attention should be given to ground water contamination, aquatic organisms and soil organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
The apparent melting point caused by loss of crystal water is given. Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. For the copper smelting sector, the EU OEL value shall apply from 11 July 2023.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 45-23/25-50/53; S: 53-45-60-61; Note: A, E

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