ICSC 0221 - ARSENIC TRICHLORIDE(OBSOLETE)

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ARSENIC TRICHLORIDE (OBSOLETE)	ICSC: 0221 (October 2000)
Arsenic III chloride Arsenous chloride

CAS #: 7784-34-1

UN #: 1560

EC Number: 232-059-5

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion on contact with water or metals.	NO contact with water or metals.	In case of fire in the surroundings, use appropriate extinguishing media.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! See Notes.
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Headache. Laboured breathing. Further see Ingestion.	Use closed system or ventilation.	Fresh air, rest. Half-upright position. Refer immediately for medical attention.
Skin	Redness. Pain.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention.
Eyes	Redness. Pain.	Wear safety spectacles, face shield or eye protection in combination with breathing protection.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	Nausea. Vomiting. Abdominal pain. Diarrhoea. Shock or collapse.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable plastic containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria Causes skin and eye irritation Causes damage to organs Causes damage to organs through prolonged or repeated exposure May cause genetic defects May cause cancer Suspected of damaging fertility or the unborn child Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: I
STORAGE
Separated from food and feedstuffs. Cool. Dry. Ventilation along the floor.
PACKAGING
Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Marine pollutant.

ARSENIC TRICHLORIDE (OBSOLETE)

ICSC: 0221

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS OILY FUMING LIQUID WITH PUNGENT ODOUR. Physical dangers Chemical dangers Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163). Reacts violently with water, moist air and strong oxidants. This produces hydrogen chloride. This generates toxic, fire and explosion hazard. Attacks many metals. This produces flammable/explosive gas (hydrogen - see ICSC 0001).	Formula: AsCl₃ Molecular mass: 181.2 Boiling point: 130.2°C Melting point: -16°C Density: 2.1 g/cm³ Solubility in water: reaction Vapour pressure, kPa at 20°C: 1.17 Relative vapour density (air = 1): 6.3 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.06 Octanol/water partition coefficient as log Pow: 1.69

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS OILY FUMING LIQUID WITH PUNGENT ODOUR.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163). Reacts violently with water, moist air and strong oxidants. This produces hydrogen chloride. This generates toxic, fire and explosion hazard. Attacks many metals. This produces flammable/explosive gas (hydrogen - see ICSC 0001).

Formula: AsCl₃
Molecular mass: 181.2
Boiling point: 130.2°C
Melting point: -16°C
Density: 2.1 g/cm³
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 1.17
Relative vapour density (air = 1): 6.3
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.06
Octanol/water partition coefficient as log Pow: 1.69

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour, by ingestion and through the skin. Effects of short-term exposure The substance is severely irritating to the eyes, skin and respiratory tract. The substance may cause effects on the gastrointestinal tract, cardiovascular system and central nervous system. This may result in severe gastroenteritis, loss of fluids and electrolytes, cardiac disorders, shock and convulsions. Exposure above the OEL could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the mucous membranes, skin, peripheral nervous system, liver and bone marrow. This may result in pigmentation disorders, hyperkeratosis, perforation of the nasal septum, neuropathy, liver impairment and anaemia. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes malformations in human babies.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, by ingestion and through the skin.

Effects of short-term exposure
The substance is severely irritating to the eyes, skin and respiratory tract. The substance may cause effects on the gastrointestinal tract, cardiovascular system and central nervous system. This may result in severe gastroenteritis, loss of fluids and electrolytes, cardiac disorders, shock and convulsions. Exposure above the OEL could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the mucous membranes, skin, peripheral nervous system, liver and bone marrow. This may result in pigmentation disorders, hyperkeratosis, perforation of the nasal septum, neuropathy, liver impairment and anaemia. This substance is carcinogenic to humans. Animal tests show that this substance possibly causes malformations in human babies.

OCCUPATIONAL EXPOSURE LIMITS
TLV: (as As): 0.01 mg/m³, as TWA; A1 (confirmed human carcinogen); BEI issued. MAK: (as As): skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A. EU-OEL: (inhalable fraction): 0.01 mg/m³ as TWA; (see Notes)

ENVIRONMENT
This substance may be hazardous to the environment. Special attention should be given to soil organisms and aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

NOTES
Specific treatment may be necessary in case of poisoning with this substance; the appropriate means with instructions should be available. The apparent melting point caused by loss of crystal water is given. Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. For the copper smelting sector, the EU OEL value shall apply from 11 July 2023.

NOTES

Specific treatment may be necessary in case of poisoning with this substance; the appropriate means with instructions should be available.
The apparent melting point caused by loss of crystal water is given.
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
For the copper smelting sector, the EU OEL value shall apply from 11 July 2023.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 23/25-50/53; S: (1/2)-20/21-28-45-60-61; Note: A

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